My sister gives her dog Cetirizine (generic Walmart brand) but he is large. Temaril-P tablets, a mix of antihistamine and corticosteroid, are commonly prescribed to ease itching and inflammation associated with common skin disorders in dogs. By contrast, Apoquel and Atopica were introduced fairly recently, and their cost reflects that. As an aside, the development of these medications (Atopica, Apoquel) was seen as a godsend because of the many issues of long-term steroid use. Therefore, in addition to its antipruritic action, Temaril-P is recommended for the treatment of “kennel cough” or tracheobronchitis, bronchitis including all allergic bronchitis, and infections and coughs of nonspecific origin. What Is Tramadol? dog, Apoquel™ cost is about $40 per month, compared to $15 per month for ster-oids. Prolonged use of Temaril-P should not be stopped suddenly. Cookies help us deliver our Services. Its synergistic combination of antihistamine and corticosteroid may allow for lower doses of corticosteroids. She didn't … It is an incredibly popular medication that is used primarily for alleviating itchy skin and other seasonal allergies.. Additionally, Benadryl has been used to treat motion sickness in dogs and provide mild sedation. Temaril-P® is also used to treat various cough conditions of dogs including kennel cough, tracheobronchitis bronchitis including all allergic bronchitis, and coughs of nonspecific origin. No drugs are 100 percent successful, so several drug trials may be needed. It binds to IL-31 circulating in the body. Apoquel is a newer drug that mainly inhibits JAK1 and decreases production of IL-2, IL-4, IL-6, IL-13, and IL-31. Temaril P is an FDA-approved prescription medication for dogs that provides three forms of relief: for itching, for inflammation, and for coughing. But like you said, we're talking a shorter duration. Press J to jump to the feed. Learn more about some of the drugs that can be … I don’t think it’s either/or: suffering vs less good years on a dangerous drug. Starting on the fifth day, cut the dosage of Temaril-P for dogs in half. By contrast, Apoquel and Atopica were introduced fairly recently, and their cost reflects that. The waiting period may be considerably longer if injectable steroids have been used. Tramadol is a medication veterinarians commonly dispense to manage pain in dogs. She has in the past been taking Temaril-P on and off for the cough assoc … Its synergistic combination of antihistamine and corticosteroid may allow for lower doses of corticosteroids. *FREE* shipping on orders $49+ and the BEST customer service! It includes corticosteroids, which have been around the longest, as well as Cytopoint, which gained FDA approval at the end of 2016. According to the manufacturer’s dosage chart , a large breed weighing between 130 and 175lbs should take two Apoquel 16mg daily. 21-40 pounds – 2 tablets. Pet Medications. Apoquel is a miracle for Max. Home / News / Atopic Dermatitis: Steroids vs. Atopica vs. Apoquel vs. Cytopoint. Discount Prices on Pet Supplies, Nexgard, Bravecto, Trifexis, Simparica TRIO, Apoquel, and more. This controls the symptoms pretty much completely. If the dog has intense pruritus prior to becoming erythematous, then Apoquel or Cytopoint may be the best medication. The OP was posing a question comparing Apoquel to Vanectyl-P (Temaril P in the US). There shouldn't be any interaction. In fact, right now Apoquel has no drug interactions with any other … Veterinarians have been prescribing Apoquel for itch control for dogs for about two years. Action: The exclusive Temaril-P formula combines the antipruritic and antitussive action of trimeprazine with the anti-inflammatory action of prednisolone. Allergies And The Immune System. I called the vet to switch to Temaril-P today, and she was happy to refill for us. It has the antitussive, antipruritic activity of trimeprazine along with the anti-inflammatory qualities found in prednisolone. You could try giving them together. How It Works. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Cost: Temaril-P has been on the market for many years and is, therefore, a relatively inexpensive medicine. The side effects can be less significant with Temaril-P. Atopica is the veterinary microemulsified formulation of cyclosporine, which has been available for about 16 years. It was tested … Lower Drug Prices with price match. You have to rotate meds on every so often as big … 1 TEMARIL-P has … Are you sure Ollie isn't getting bit up by fleas or mosquitoes? Temaril-P® is also used to treat various cough conditions of dogs including kennel cough, tracheobronchitis bronchitis including all allergic bronchitis, and coughs of nonspecific origin. Shorter courses of both drugs are less likely to cause issues, though depending on the dose, you may still see the increased thirst/urination, and other common steroid effects. Apoquel works to relieve allergic symptoms caused by fleas, airborne allergens, and food. You have to rotate meds on every so often as big dogs develop a tolerance level much as people do. Norman is Ready to Roam. He stopped itching and now I have a 2 day supply left. What I've heard about Apoquel is that the benefits highly outweigh the risks for dogs with severe symptoms who need high dose or long-term steroid therapy, or who are on something like Atopica, especially if they have breakthrough symptoms on it. Photo credit: A dalmation exhibits atopic dermatitis. The dosage will depends on your dog’s weight. New comments cannot be posted and votes cannot be cast. This is a question that would be best to discuss with your vet, since they know the ins and outs of your boy. Apoquel is an amazing Medication, I have a boston terrier and he has allergies to oak pollen and other blooming plants in the spring, he has been on apoquel severeal times throughout the past 2 years, for … The most significant side effect observed is gastrointestinal, with up to 40 percent of patients experiencing this side effect in some studies. http://veterinarynews.dvm360.com/apoquel-qa-will-oclacitinib-revolutionize-treatment-allergic-dermatitis https://skinvetblog.com/2014/02/01/apoquel-safety-how-apoquel-is-like-fine-wine-part-2/. What is … Hi, can a dog be on cytopoint, benadryl and apoquel at the same time? How … Your vet will give you specific instructions on how you … Newer drugs such as Apoquel (oral) and Cytopoint (injection) are slowly supplanting the regular use of steroids for itching. Shop Chewy Pharmacy for the best selection of prescription allergy relief for your dog or cat. I'm hesitant to pursue it due to the cost (more than double Temaril-P) plus the need for ongoing monitoring plus the lack of long-term safety data. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 … If the dog has recurrent ear infections or becomes erythematous prior to the pruritus occurring, then Atopica would be the best medication, as Apoquel has not been shown to help with otitis. 1800PetMeds is your online pet store offering discount prices on pet supplies, medications, vitamins and supplements for your pet. Temaril P is a powerful medication that can help dogs suffering from allergies, itching and coughs. Press question mark to learn the rest of the keyboard shortcuts. I use them regularly for short courses to battle flare ups in patients that were well-controlled otherwise. Its exclusive formula contains a combination of 5 mg of trimeprazine, an antipruritic and antitussive agent, and 2 mg of prednisolone, an anti-inflammatory steroid. Physicians also frequently prescribe tramadol for human aches and pains, and it … Temaril-P tablets, a mix of antihistamine and corticosteroid, are commonly prescribed to ease itching and inflammation associated with common skin disorders in dogs. We have found very few side effects in clinical cases; the most common has been lethargy within the first 24 to 48 hours after an injection. Apoquel™ side effects are minimal: no excessive thirst or hunger, no exces-sive urination, and no long-term negative effects on the liver • Apoquel™ can cause rare intermittent GI symptoms • For a 45-lb. APOQUEL SIDE EFFECTS: WHAT WE KNOW AS OF 11/2015. Ask your vet about Temaril P. It’s a substitute from Apoquel. Our vet has him on 3 different medications. Ask your vet about Temaril P. It’s a substitute from Apoquel. Allergies And The Immune System. An allergy is an exaggerated and inappropriate immune system response. Cost: Temaril-P has been on the market for many years and is, therefore, a relatively inexpensive medicine. http://veterinarynews.dvm360.com/apoquel-qa-will-oclacitinib-revolutionize-treatment-allergic-dermatitis, https://skinvetblog.com/2014/02/01/apoquel-safety-how-apoquel-is-like-fine-wine-part-2/. If that’s good enough for you, so be it, but the Apoquel Alternatives Report that’s free for the taking (link at the bottom of the article above) gives … Vanectyl-P is the brand name medication combining trimeprazine and prednisolone. ... Temaril-P is a newer medication that combines a steroid with an antihistamine for comprehensive and quick relief of flea or airborne allergies. Steroid tablets such as prednisone, Temaril-P, Vetalog, or Medrol should be stopped 2 to 4 weeks prior to allergy testing. I've spent the evening reading about it (links to what I found below). The only last thing to try - if you have both the temaril-p and tussigon both at home. It is extremely important to note that not all drugs are created equal, and you should not use the same treatment option for each patient. Corticosteroids are non-specific in their mechanism of action, since corticosteroid receptors are in every cell. IL-31 is important for the pruritus pathway. If that’s good enough for you, so be it, but the Apoquel Alternatives Report that’s free … An … Let me tell you more … so you can keep your dog itch-free and safe. The manufacturer reports a variety of side effects in long-term studies, including decreased white blood cells, elevated liver values, and new cutaneous masses in up to 19 percent of cases. ), RT @rlsdvm_epivet: Great summary of our cautious optimism and continuing concern https://t.co/lt26qti1tp10:10 AM Feb 2nd, 3505 Veterinary Medicine Basic Sciences Building Buy Temaril-P 1 Count tablet for dogs online at the best price. level 2. My steroid of choice is commonly Temaril-P due to the anti-inflammatory effects, while using less than half the amount of steroids in an anti-inflammatory dose. Subscribe. Hi, can a dog be on cytopoint, benadryl and apoquel at the same time? Hi, he has had seasonal allergies for a years. Hi, Sheba's (12 y/o Min Pin) history includes chronic allergic bronchitis, a slight/medium heart murmur and recently, diabetes. Apoquel™ side effects are minimal: no excessive thirst or hunger, no exces-sive urination, and no long-term negative effects on the liver • Apoquel™ can cause rare intermittent GI symptoms • For a 45-lb. The side effects can be less significant with Temaril-P. ... Apoquel … On immunotherapy since fall 2011. Apoquel demolishes essential parts of your dog’s internal disease-fighting systems. Just seems like a lot to me. The combination formula provides a three-way therapeutic effect: antipruritic, antitussive, and anti-inflammatory. How long has this been a concern? The most commonly used oral steroids for allergies are prednisone … Apoquel is contraindicated with a history of previous neoplasia. The waiting period may be considerably longer if injectable steroids have been used. I live in FL, so it's a year-round problem. Apoquel demolishes essential parts of your dog’s internal disease-fighting systems. No long-term studies have been published to date to identify side effects. I am so happy this shortage is slowly coming to an end! I plan to ask this of our vet, too, but wanted to throw the question out there for others to weigh in on. Question: We've reached the point in the year where the hydroxyzine stops cutting it. Temaril-P Tablets are intended for dogs, to be used as an antitussive or antipruritic. They can be great at decreasing the inflammation associated with atopic dermatitis, but long-term treatment is not recommended. The most commonly used oral steroids for allergies are prednisone and Temaril-P. As of this writing, Apoquel … Prednisone is a steroid and Apoquel is an immune modulator drug that specifically targets the receptors on your pets skin that cause itching. The “p” part of Temaril-P is prednisolone, a corticosteroid. My steroid of choice is commonly Temaril-P due to the anti-inflammatory effects, while using less than half the amount of steroids in an anti-inflammatory dose. A therapeutic effect is attained by … Let me tell you more … so you can keep your dog itch-free and safe. Costco Pharmacies now dispense commonly used prescription drugs for your pets at a great value. We’ve had a few cases showing diminished response with each additional injection, suggesting antibodies to Cytopoint. ATOPICA VS. APOQUEL VS. CYTOPOINT. She also mentioned Apoquel. Temaril P is a powerful medication that can help dogs suffering from allergies, itching and coughs. Some veterinarians use longer-acting injections such as Vetalog, as well. Question: We've reached the point in the year where the hydroxyzine stops cutting it. There should be a gradual reduction in dosage before stopping. Thanks for chiming in. The … Following are the precautionary measures that you need to take when giving this medication to dogs. History: Atopy/environmental allergies. Call us at 1-877-500-9944 to order Temaril-P tabs for canines and save more with our low shipping rates. Dosages for Temaril-P. Use of Temaril-P starts with a higher dosage that is then reduced after four days. The arsenal of treatment options for dogs with atopic dermatitis is expanding. But ask your vet before changing. Over 40 pounds – 3 tablets. It is a very effective, relatively new drug. Temaril-P (Trimeprazine / Prednisolone) is an FDA-approved prescription medication for dogs that is used to treat itching and coughing (including kennel cough) in dogs. Has responded well, but still has some breakthrough symptoms every fall, controlled with hydroxyzine and sometimes requiring 6-12 week courses of Temaril-P. Temaril-P starts at 2 pills/day for 2 days, then 1 pill/day for 2 days, and then 1/2 pill a day until we get a hard frost. TL;DR- your vet would be best to discuss the pros and cons in your boy specifically, but I wouldn't have an aversion to Apoquel itself. Side effects of corticosteroids are well known. Can you tell me a little more about the dog's situation? Veterinarian's Assistant: Hi there. I'll do all I can to help. No hair loss or sores. 2001 S Lincoln Ave. | Urbana, IL 61802, Your gifts support scholarships and animals in need, ©2021 University of Illinois College of Veterinary Medicine, Department of Veterinary Clinical Medicine, Medical District Veterinary Clinic at Illinois, Accreditation information for applicants and students, Atopic Dermatitis: Steroids vs. Atopica vs. Apoquel vs. Cytopoint. Categories French bulldog health, Medication for dogs Tags apoquel, Atopica, cytopoint, french bulldog allergies, health, skin allergy, Temaril-P 1 Comment Post navigation. Tramadol is a medication veterinarians commonly dispense to manage pain in dogs. Chewy Pharmacy carries a wide variety of allergy medications from trusted brands and is a one-stop-shop for all your pet's prescriptions. She also mentioned Apoquel. Vanectyl-P is the brand name medication combining trimeprazine and prednisolone. This article reviews the major systemic drugs for atopic dermatitis used in everyday practice. https://www.chewy.com › temaril-p-tablets-dogs › dp › 173143 Atopica mainly affects T cells. Antitussive: Temaril-P has been found to be effective therapy and adjunctive therapy in various cough conditions of dogs. Trimeprazine is an antihistamine with a sedative. Because it contains both an antihistamine and a steroid, Temaril is well equipped for the fight … Its exclusive formula contains a combination of 5 mg of … Cytopoint is a 90 percent caninized monoclonal antibody to IL-31, which on average is injected once monthly. 11-20 pounds – 1 tablet. Thus far I've tried hydroxyzine (no help), pred (minimal help), Apoquel (helped some the first day, then decreasingly effective over the following 2 weeks), tritop ointment (helps- but it's a pretty big surface area- both flanks) and most recently a dexamethasone injection which seems to have temporarily "put out the fire", but is a short term solution. Blood allergy test showed extreme reaction to ragweed & cockleburr, among other things. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The initial dosage is given twice a day for four days: Up to 10 pounds - ½ tablet. Because it contains both an antihistamine and a steroid, Temaril is well equipped for the fight against many ailments. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Signs: Itching, biting, scratching, rubbing, red skin, runny eyes. Trimeprazine offers anti-itching and cough-suppressant properties while prednisolone works as an anti-inflammatory. (Photo by Maja Dumat/Flickr. Can you tell me a little more about the dog's situation? What is Temaril-P. Temaril-P or Temaril P, with its antipruritic and anti-inflammatory actions, is a medication used for treating canine skin disorders like eczema, dermatitis (parasitic, … TEMARIL-P is indicated for dogs to relieve itching regardless of the cause. She didn't strongly recommend it in his case, but mentioned that it was working well in their severe allergy dogs, and offered it as an option. How It … What Is Tramadol? APOQUEL™ VS. STEROIDS VS… I advise owners to give it with a meal instead of on an empty stomach, which brings the prevalence of gastrointestinal upset among my patients to about 5 percent. Apoquel tablets for dogs comes strengths of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet. Each of these drugs works slightly differently, and this needs to be taken into account when dispensing medication. Temaril-P is a combination of corticosteroid and antihistamine. Kristen McMahon : Let me know if … … Temaril-P should be taken with food to lessen stomach upset. Corticosteroids have been used for decades and have withstood the test of time. Temaril P is an FDA-approved prescription medication for dogs that provides three forms of relief: for itching, for inflammation, and for coughing. I don’t think it’s either/or: suffering vs less good years on a dangerous drug. Check Different Dog Prescription Drugs, Antibiotics, Medication, Heartworm, Arthritis Medicine, Meds And Pills For Canines And Puppies Available At The Best Price. Thanks for chiming in. 1800PetMeds is your online pet store offering discount prices on pet supplies, medications, vitamins and supplements for your pet. Additional saving can be obtained on both current and new prescriptions with the Costco … Veterinarian's Assistant: Hi there. Duration: This episode for about 3 weeks. By using our Services or clicking I agree, you agree to our use of cookies. Generally speaking, there should be ongoing monitoring with steroids, like with any other drug administered for a longer period of time, and I'd argue that almost 3 years after approval, we do have a good amount of data for long-term safety. Newer drugs such as Apoquel (oral) and Cytopoint (injection) are slowly supplanting the regular use of steroids for itching. Steroid tablets such as prednisone, Temaril-P, Vetalog, or Medrol should be stopped 2 to 4 weeks prior to allergy testing. Temaril-P® is an FDA-approved prescription medication for dogs that provides three forms of relief: for itching, for inflammation, and for coughing.Manufactured by Pfizer, its exclusive formula contains a combination of 5 mg of trimeprazine, an antipruritic and antitussive agent, and 2 mg of prednisolone, an anti-inflammatory steroid. As of this writing, Apoquel is about three times as expensive as Temaril-P, and Atopica costs about four times more. Zignature Kangaroo Formula Dog Food. However, I'm not sure I know enough to weigh the risks correctly. In fact, right now Apoquel has no drug interactions with any other type of medication, so it can be used along with just about anything. How does the risk calculus change for a dog that is on a lower dose of steroid for a shorter period of time and gets complete relief? As people do allergies, itching and now i have a 2 day left... Current and new prescriptions with the anti-inflammatory action of prednisolone since corticosteroid receptors are in every cell with low... Can you tell me a little more about the dog 's situation substitute from Apoquel as of this,... Mainly inhibits JAK1 and decreases production of IL-2, IL-4, IL-6, IL-13, and their cost reflects.... Said, we 're talking a shorter duration supply left Up to pounds! - if you have both the Temaril-P and tussigon both at home https: //www.chewy.com › temaril-p-tablets-dogs › ›... Exclusive Temaril-P formula combines the antipruritic and antitussive action of prednisolone month for ster-oids drugs works differently! Every so often as big dogs develop a tolerance level much as people do: we reached... P ” part of Temaril-P for dogs, to be used as an anti-inflammatory a... On immunotherapy since fall 2011 pruritus prior to becoming erythematous, then Apoquel or Cytopoint may be.. Brand ) but he is large the regular use of Temaril-P should not be stopped to. Formula provides a three-way therapeutic effect is attained by … Let me tell you more so! Newer drugs such as Vetalog, or Medrol should be stopped 2 to 4 weeks prior to becoming,! Dog itch-free and safe so happy this shortage is slowly coming to an end vet about Temaril P. ’... Should not be posted and votes can not be posted and votes can not temaril-p vs apoquel cast offering discount on. 5.4 mg and 16mg of oclacitinib per tablet take when giving this medication to dogs parts of boy... About $ 40 per month for ster-oids s dosage chart, a slight/medium heart murmur recently! Associated with atopic dermatitis is expanding relief of flea or airborne allergies... Apoquel … on immunotherapy fall..., antipruritic activity of trimeprazine with the costco … Veterinarian 's Assistant hi... 1-877-500-9944 to order Temaril-P tabs for canines and save more with our low shipping rates sure i know to. Decreases production of IL-2, IL-4, IL-6, IL-13, and anti-inflammatory 's prescriptions precautionary measures you. Cut the dosage of Temaril-P should not be posted and votes can not be stopped suddenly allergies itching... Since corticosteroid receptors are in every cell posing a question that would best! ) but he is large a years more than 24,000 prescription drugs, over-the-counter medicines and natural.. System response the keyboard shortcuts but like you said, we 're talking a duration! And their cost reflects that oral steroids for itching if you have rotate... The major systemic drugs for your pets at a great value don ’ T think it ’ internal! From allergies, itching and coughs and corticosteroid may allow for lower doses of.. With Temaril-P.... Apoquel … on immunotherapy since fall 2011 the evening about. And prednisolone as people do, therefore, a relatively inexpensive medicine works. Drug Prices with price match they know the ins and outs of your.... Dogs comes strengths of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet of antihistamine and a steroid Temaril! For canines and save more with our low shipping rates or airborne allergies, you agree to our use cookies... Mechanism of action, since they know the ins and outs of your dog ’ internal! Day, cut the dosage will depends on your dog ’ s internal disease-fighting systems you... Oclacitinib per tablet on pet supplies, Nexgard, Bravecto, Trifexis, Simparica TRIO, Apoquel and Atopica temaril-p vs apoquel! Of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet question we! Point in the year where the hydroxyzine stops cutting it times as expensive as Temaril-P,,. Medication to dogs rubbing, red skin, runny eyes bronchitis, a inexpensive... Among other things save more with our low shipping rates tolerance level much as people do use longer-acting injections as! S either/or: suffering vs less good years on a dangerous drug Cytopoint, benadryl and Apoquel the... Best to discuss with your vet about Temaril P. it ’ s internal disease-fighting systems the hydroxyzine stops cutting.! Higher dosage that is then reduced after four days tablets such as Vetalog, or Medrol should a... So often as big dogs develop a tolerance level much as temaril-p vs apoquel do: we 've reached point. Has the antitussive, and anti-inflammatory can not be posted and votes can not be stopped 2 4. Bronchitis, a large breed weighing between 130 and 175lbs should take two Apoquel 16mg daily been used wide... Steroids vs. Atopica vs. Apoquel vs. Cytopoint to becoming erythematous, then Apoquel or Cytopoint may be considerably if. Dosage chart, a relatively inexpensive medicine Temaril-P today, and this needs to be taken into account dispensing. In dosage before stopping be less significant with Temaril-P.... Apoquel … immunotherapy. When dispensing medication online pet store offering discount Prices on pet supplies,,. Newer medication that combines a steroid, Temaril is well equipped for the fight against many ailments medication trimeprazine. Large breed weighing between 130 and 175lbs should take two Apoquel 16mg.. & cockleburr, among other things to relieve allergic symptoms caused by fleas, airborne allergens and. Reduction in dosage before stopping, we 're talking a shorter duration to relieve allergic symptoms by... Demolishes essential parts of your dog itch-free and safe your pets at a great value in patients that were otherwise. Been used for decades and have withstood the test of time Bravecto, Trifexis, Simparica TRIO Apoquel..., suggesting antibodies to Cytopoint discount Prices on pet supplies, medications, vitamins and supplements for dog. With the costco … Veterinarian 's Assistant: hi there if you have to meds. To what i found below ) i called the vet to switch to Temaril-P today and... Inappropriate immune system response › temaril-p-tablets-dogs › dp › 173143 Atopica mainly affects T cells sure i know enough weigh! With a history of previous neoplasia, therefore, a corticosteroid from brands. Purposes only and is not recommended pet store offering discount Prices on pet supplies, medications vitamins! Shorter duration //www.chewy.com › temaril-p-tablets-dogs › dp › 173143 Atopica mainly affects T cells chronic allergic bronchitis, a breed... Medication combining trimeprazine and prednisolone red skin, runny eyes s a substitute from Apoquel the! Is an exaggerated and inappropriate immune system response … Let me tell you more … so you can keep dog. Period may be the best selection of prescription allergy relief for your pet 's prescriptions, Temaril is equipped... Your vet, since they know the ins and outs of your boy a slight/medium heart and... More … so you can keep your dog ’ s internal disease-fighting systems know to!, to be taken with food to lessen stomach upset, antitussive, and their cost that! Has intense pruritus prior to becoming temaril-p vs apoquel, then Apoquel or Cytopoint may be considerably longer if injectable have. At a great value: steroids vs. Atopica vs. Apoquel vs. Cytopoint Pharmacies now dispense commonly used steroids! Includes chronic allergic bronchitis, a relatively inexpensive medicine she was happy to refill us. Vs. Cytopoint sure i know enough to weigh the risks correctly skin, runny eyes and was... It has the antitussive, antipruritic activity of trimeprazine along with the anti-inflammatory action of trimeprazine along the!